Professor of Pathobiology

Education: Ph.D., Washington State University (College of Veterinary Medicine), DVM, Washington State University (College of Veterinary Medicine), MS, Washington State University (College of Veterinary Medicine), BS, Washington State University (Department of Zoology)

Biography

Dr. Laegreid’s research interests are focused on the pathogenesis and control of animal diseases, especially high consequence infections of livestock. He utilizes molecular, cellular, animal and population based studies to elucidate mechanisms of injury and susceptibility to viral and bacterial disease. Dr. Laegreid’s recent work is directed towards understanding the how genomic variation of hosts and pathogens interacts to influence the expression of disease at the population level. Dr. Laegreid is the author or co-author of over 75 peer reviewed scientific publications, as well as contributions to books, reports and other publications.

Dr. Laegreid obtained his BS, MS, DVM and PhD degrees from Washington State. In addition he completed a residency in anatomic pathology in the Washington Animal Disease Diagnostic Laboratory. After moving to the Plum Island Animal Disease Center he became Research Leader of the Molecular Pathology Unit, initiating pathogenesis and vaccine research primarily on arthropod borne transboundary diseases such as African horsesickness and Venezuelan equine encephalitis, as well as working with other exotic diseases such as African swine fever, and foot-and-mouth disease. Dr. Laegreid became Research Leader of the Animal Health Unit at the U.S. Meat Animal Research Center where he led research programs on zoonotic foodborne pathogens, and genomics of livestock disease, including E. coli O157:H7 and bovine spongiform encephalopathy. In 2007, he became a professor in the faculty of the Department of Pathobiology, College of Veterinary Medicine at the University of Illinois Urbana-Champaign.

Selected Publications

Articles or Book Chapters:

Bono, JL, J.E. Keen, M.L. Clawson, M.P. Heaton, W.W. Laegreid. 2007. Association of specific tir alleles in Escherichia coli O157:H7 with virulence in humans. BMC Infectious Disease 7:98.

Laegreid, W.W. Porcine reproductive and respiratory syndrome, Proceedings of the 57th Annual Meeting of the American College of Veterinary Pathologists, 2006.

Clawson, ML, M.P. Heaton, J.W. Keele, W.W. Laegreid. 2006. Linkage disequilibrium and haplotype structure in the prion gene of U.S. beef and dairy cattle. BMC Genetics, 7(1):51.

Chang ACY, L. Zsak, Y. Feng, R. Mosseri, Q. Lu, P. Kowalski, W.W. Laegreid, D.L. Rock, and S.N. Cohen. 2006. Phenotype-Based Identification of Host Genes Required for Propagation of African Swine Fever Virus, J. Virol. 80(17):8705-8717.

Green BT, M.P. Heaton, M.L. Clawson, C.G. Chitko-McKown, W.W. Laegreid. 2006. Linkage disequilibrium across six prion gene regions spanning 20 kbp in U.S. sheep. Mammalian Genome 17(11):1121-9.

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Link(s)

http://www.cvm.uiuc.edu/faculty/path/laegreid.html

Contact Information

Office

2414 Veterinary Medicine Basic Sciences Building

Mailing Address

2001 S. Lincoln Ave.
Urbana, IL 61802
MC-002

Phone

(217) 244-8524

Email

laegreid[AT]uiuc[DOT]edu